filling machine

Isolator Technology

Safety and performance from one source – with more than 25 years of experience

The safe economical filling of aseptic and highly potent products requires comprehensive process knowledge. Bosch has decades of experience in the design and manufacture of isolators and complete production lines, with references from pharmaceutical customers all over the world. We offer you a unique integration approach – ranging from the isolator itself, to the bio-decontamination and air-handling technology to the qualification and validation of the entire system – all from one source.

Your advantages

  • Integration instead of interfaces
    • More than 25 years of experience in designing isolator lines
    • All elements of the isolator line from one source
    • Filling machine, isolator, air handling as well as process technology
    • Common integrated start-up (integrated FAT) of entire line
  • High potent applications
    • Special isolator design and pressure concepts for applications up to OEB6
    • Dedicated filter systems for potent applications
    • System optimization for critical processing areas of both filling machine and isolator
    • Continuous research on cleaning and washdown processes including automation concepts
  • Short cycle times for biodecontamination
    • Bosch own developed biodecontamination system SafeVAP
    • Shortest cycle times down to <1 hour for entire filling lines
    • Bosch own catalytic converter technology for optimized aeration concepts
    • Dedicated process development team
  • Microbiological expertise
    • Research and services for isolator and process technology
    • PharmaLab cleanroom facility as part of our global R&D laboratory expertise
    • Topics around biological indicators including microbial identification, spore count and D-value determination
    • Qualification and validation support including cycle development and revalidation
  • Barrier systems competence
    • Coverage of entire barrier systems portfolio including open RABS, closed RABS, containments and isolators
    • Supporting equipment like H2O2 transfer chambers, wireless glove testing systems, cleaning systems, etc.
    • Integration of components and machines from third party manufacturers

Customer support and service

Customer support and service graphic

Bosch offers you entire lifecycle support for isolator systems. Starting with project consulting covering your needs and expectations, up to machine design and development to the on-site installation, validation and H2O2 cycle development.


Matthias Angelmaier

Get in touch with an expert

We´re looking forward to getting in contact with you and providing further information about isolator technology. Please contact:

Matthias Angelmaier 
Product manager for barrier systems and isolator technology
Phone +49 7951 402-7944

E-mail